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I had previously taken Quinine when traveling to areas with malaria. Every time the medication worked flawlessly, well at least I have had no cases of malaria. And other people, whom I know travelling to Africa and countries with possible infection risk, also vote for Quinine as an effective medication. It was my family physician who advised me to take the drug, and I am grateful to him for the piece of advice. I have heard of horrible side effects people have with other meds for malaria prevention and treatment. With Quinine everything goes absolutely smoothly and trouble-free, at least in my case it was like this. In other words, I consider Quinine to be a very effective medication for its purpose and I would recommend other travellers to use it.

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I last used Quinine about three years ago on a trip to India, it was our honey moon destination. Such countries with tropical climate are well-known for the risk of malaria for tourists from other regions. Every person who travels there should take preventive measures to avoid the disease. I am strongly convinced that is this medication that prevented me from getting malaria. The only side effect was strange taste, or better to say lack of any taste at all during the first day after starting the treatment. But then everything got back to normal. My husband also took Quinine before the departure and he's health is absolutely ok as well. I think Quinine does its job.

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Looareesuwan S, Charoenpan P, Ho M, White NJ, Karbwang J, Bunnag D, Harinasuta T: Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment.

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Quinine tablets require a prescription, but quinine and the product from which it is derived, cinchona, are also available without prescription.

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Because of increasing reports of severe reactions to quinine and the absence of evidence for its efficacy in the treatment of leg cramps, over-the-counter marketing of quinine was banned by the US Food and Drug Administration (FDA) in 1994 ().

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Malarone is only effective if it has not been used as a prophylactic beforehand (as in your case, since you had been taking mefloquine) so it is good to see that your clinicians took this into consideration.

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Of the 14 patients with any neurological sequelae who did not have cerebral malaria initially (ten artesunate, four quinine), seven had multiple convulsions (three quinine, four artesunate) and all had severe prostration on admission.

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Meanwhile in Brazil, the supremacy of preventive approaches which focused primarily on the vector of malaria (adopted in the campaigns started by the Rockefeller Foundation after the First World War) put strategies designed to address the parasite, and the preventive and therapeutic use of quinine on the back burner.

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Medscape: In 2010, the Therapeutics and Technology subcommittee of the American Academy of Neurology conducted an evidence-based review of the literature examining use of quinine for the off-label management of leg cramps.

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