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FDA evaluated a pooled analysis of randomized clinical trials and found that heart failure was more frequent with pramipexole than with placebo; however, these results were not statistically significant.
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It is not clear why pathological gambling is positioned with impulse control disorders in the DSM-IV, since there appears to be more similarities between pathological gambling and substance-related disorders than there are between pathological gambling and impulse-control disorders, at least in terms of their diagnostic criteria.
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Food and Drug Administration (FDA) has approved Mirapex ER速 (pramipexole dihydrochloride) extended-release tablets, a new once-daily treatment option for the signs and symptoms of early idiopathic Parkinson's disease (PD).
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